Diazepam is N-demethylated by CYP3A4 and 2C19 for the active metabolite N-desmethyldiazepam, and it is hydroxylated by CYP3A4 towards the active metabolite temazepam. N-desmethyldiazepam and temazepam are both equally even more metabolized to oxazepam. Temazepam and oxazepam are mainly eliminated by glucuronidation.
This drug may perhaps cause you to dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) may make you extra dizzy or drowsy.
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Drug interactions may perhaps adjust how your remedies get the job done or increase your chance for significant Unwanted effects. This doc does not consist of all doable drug interactions.
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FDA Commissioner Scott Gottlieb, MD, said the agency’s “hope would be that the steps we’re taking to progress this new, more modern framework will contribute to lower costs for our health care program overall and supply increased effectiveness and empowerment for people by rising The provision of specified products that would or else be offered only by prescription.”
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Diazepam has long been revealed to be able to substitute with the behavioral consequences of barbiturates inside a primate examine.[128]
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The Misuse of Medicine Act 1971 can make it illegal to possess the drug without a prescription, and for this sort of uses it is assessed as a Class C drug.[a hundred thirty five]
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